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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 392 are advancing while 4,699 are declining, suggesting a mixed market tone.

Dow Jones
52,486.49
Change
+254.6+0.49%
S&P 500
7,619.38
Change
+98.45+1.31%
Nasdaq Composite
25,466.189
Change
+400.315+1.60%
24H Gainers
392
24H Losers
4,699

52 Week Gainers

#Stock52 Week Range
4701Rapid Micro Biosystems, Inc.RPID$0.750.00%350$34.15M$0.58 - $4.940.00%
4702Vestand Inc.VSTD$0.10-44.44%2.05M$0$0.00 - $0.730.00%
4703Atossa Therapeutics, Inc.ATOS$2.20+5.52%19$21.95M$1.70 - $14.850.00%
4704NOMADAR Corp.NOMA$1.17+8.74%400$19.54M$1.01 - $10.000.00%
4705Incannex Healthcare LimitedIXHL$2.00+0.20%7.85K$25.14M$1.96 - $14.910.00%
4706Bakkt, Inc.BKKT$3.86-2.27%31.25K$61.51M$3.86 - $22.800.00%
4707ThredUp Inc.TDUP$1.45+0.07%1.27K$163.65M$1.24 - $8.760.00%
4708DarioHealth Corp.DRIO$2.10-1.41%1.61K$20.53M$1.70 - $14.770.00%
4709Context Therapeutics Inc.CNTX$0.21+3.96%3.13K$19.29M$0.18 - $3.620.00%
4710PN Smart Energy LimitedPN$2.37+0.59%1.01K$34.52M$1.77 - $40.000.00%
4711SunCar Technology Group Inc.SDA$0.33+1.24%216.08K$19.43M$0.13 - $2.450.00%
4712Anbio BiotechnologyNNNN$3.93-2.65%14$179.08M$3.09 - $44.730.00%
4713CISO Global, Inc.CISO$0.17-1.69%944$7.93M$0.15 - $1.010.00%
4714Upland Software, Inc.UPLD$3.06-2.86%121$8.69M$2.75 - $19.600.00%
4715Elicio Therapeutics, Inc.ELTX$1.59-1.12%0$45.01M$1.25 - $16.000.00%
4716Caribou Biosciences, Inc.CRBU$0.39-0.51%4.48K$42.24M$0.36 - $2.490.00%
4717Beyond Meat, Inc.BYND$5.78-1.11%9.23K$99.31M$5.51 - $44.400.00%
4718Ainos, Inc.AIMD$0.49+7.63%174.97K$3.65M$0.43 - $3.880.00%
4719American Vanguard CorporationAVD$0.87-0.02%204$25.55M$0.81 - $5.550.00%
4720Z Squared Inc.ZSQR$2.61+1.68%3.31K$138.23M$2.11 - $18.800.00%
4721ZenaTech, Inc.ZENA$0.70+0.43%16.12K$140.61M$0.58 - $5.170.00%
4722Scienture Holdings, Inc.SCNX$3.040.00%48$5.37M$2.64 - $19.470.00%
4723Ucommune International LtdUK$1.48-4.15%516$985.70K$1.39 - $10.500.00%
4724Neumora Therapeutics, Inc.NMRA$0.48+7.08%10.16K$90.94M$0.32 - $3.650.00%
4725Amesite Inc.AMST$0.49-1.21%858$3.20M$0.46 - $3.050.00%
4726Conexeu Sciences Inc.CNXU$2.20-6.14%174$71.84M$2.01 - $18.790.00%
4727FuboTV Inc.FUBO$7.92-0.13%963$239.22M$7.44 - $47.400.00%
4728Expion Energy, Inc.XPON$2.550.00%51$2.58M$2.26 - $19.200.00%
4729Presidio Property Trust, Inc.SQFT$0.85-6.48%1.26K$1.22M$0.72 - $5.181.09%
4730BioNexus Gene Lab Corp.BGLC$0.81-8.93%1.03K$2.36M$0.80 - $5.130.00%
4731loanDepot, Inc.LDI$0.48+1.67%33.89K$112.15M$0.45 - $3.240.00%
4732Greenland Energy CompanyGLND$2.15+0.23%20.28K$101.45M$1.09 - $23.000.00%
4733Compass Therapeutics, Inc.CMPX$0.81+0.25%2.79K$145.69M$0.67 - $6.880.00%
4734Dominari Holdings Inc.DOMH$0.90+1.01%15$21.82M$0.70 - $5.711.16%
4735Anebulo Pharmaceuticals, Inc.ANEB$0.000.00%0$0$0.00 - $2.490.00%
4736Greenland Mines LtdGRML$3.84-2.54%16.42K$52.58M$2.82 - $27.480.00%
4737Change Agents CorporationCHGA$0.89+0.91%116$995.87K$0.69 - $5.740.00%
4738Thryv Holdings, Inc.THRY$1.03+7.89%628$45.59M$0.90 - $6.390.00%
4739IQSTEL INC.IQST$0.790.00%1.45K$8.63M$0.73 - $5.170.00%
4740LENZ Therapeutics, Inc.LENZ$4.17+0.39%597$130.87M$2.80 - $32.130.00%
4741PAVmed Inc.PAVM$1.87+27.75%27$14.94M$1.17 - $28.440.00%
4742Barfresh Food Group Inc.BRFH$0.49-1.60%11.22K$8.04M$0.42 - $3.500.00%
4743Corteva, Inc.CTVA$10.65-11.61%323.53K$7.10B$10.63 - $90.970.06%
4744Revelation Biosciences, Inc.REVB$4.40+7.95%149$2.34M$3.08 - $40.600.00%
4745BeneficientBENF$0.68-3.00%12.25K$12.85M$0.50 - $9.960.00%
4746Hadron Energy, Inc.HDRN$0.64-3.62%645$45.69M$0.60 - $5.400.00%
4747Organogenesis Holdings Inc.ORGO$1.02-5.54%1.71K$131.76M$0.73 - $6.560.00%
4748MBody AI Ltd.MBAI$2.04-6.61%34$31.14M$1.61 - $27.440.00%
4749Nyxoah SANYXH$0.92+2.12%1.25K$91.05M$0.80 - $5.920.00%
4750DEFSEC Technologies Inc.DFSC$0.50-5.09%2.81K$2.31M$0.49 - $5.090.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Rapid Micro Biosystems, Inc. (RPID) currently leads with a 52-week gain of 81.93% as of 2026-11-12 13:59 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.