Dow Jones
52,486.49
Change
+254.6+0.49%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are mixed today. The Dow Jones is +0.49%, the S&P 500 is +1.31%, and the Nasdaq Composite is +1.60%. Across individual stocks, 304 are advancing while 4,786 are declining, suggesting a mixed market tone.
S&P 500
7,619.38
Change
+98.45+1.31%
Nasdaq Composite
25,466.189
Change
+400.315+1.60%
24H Gainers
304
24H Losers
4,786
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 1 | Eloxx Pharmaceuticals, Inc.ELOX | $12.95 | +3.60% | 23.48K | $52.29M | $12.50 - $23.40 | 0.00% |
| 2 | Mega Fortune Company LimitedMGRT | $115.37 | 0.00% | 596 | $1.63B | $4.04 - $170.00 | 0.00% |
| 3 | Nine Energy Service, Inc.NINE | $7.49 | +1.99% | 0 | $93.05M | $0.29 - $13.23 | 0.00% |
| 4 | Bank of New York Mellon CorporationBNY | $153.61 | +0.26% | 143 | $103.37B | $10.05 - $165.84 | 0.02% |
| 5 | TJGC Group LimitedTJGC | $31.64 | -3.18% | 68.09K | $319.51M | $1.46 - $36.76 | 0.00% |
| 6 | Moderna, Inc.MRNA | $239.50 | -2.44% | 105.24K | $95.62B | $22.28 - $280.80 | 0.00% |
| 7 | agilon health, inc.AGL | $115.65 | +0.78% | 1.63K | $1.94B | $7.48 - $133.04 | 0.00% |
| 8 | Climb Bio, Inc.CLYM | $12.77 | +3.56% | 1.42K | $736.90M | $1.64 - $18.33 | 0.00% |
| 9 | Erasca, Inc.ERAS | $17.08 | -1.18% | 2.67K | $5.97B | $2.34 - $24.28 | 0.00% |
| 10 | SELLAS Life Sciences Group, Inc.SLS | $8.38 | +0.30% | 21.38K | $1.69B | $1.39 - $15.88 | 0.00% |
| 11 | Kodiak Sciences Inc.KOD | $109.83 | +0.77% | 479 | $6.90B | $18.05 - $112.31 | 0.00% |
| 12 | Space Exploration Technologies Corp.SPCX | $137.69 | -0.30% | 2.08M | $1.93T | $21.32 - $225.64 | 0.00% |
| 13 | CareDx, Inc.CDNA | $81.92 | -0.59% | 2.23K | $4.30B | $15.15 - $90.87 | 0.00% |
| 14 | Vince Holding Corp.VNCE | $13.28 | -0.77% | 188 | $171.92M | $1.95 - $13.90 | 0.00% |
| 15 | New Century Logistics (BVI) LimitedNCEW | $16.72 | +1.06% | 101 | $53.51M | $2.80 - $20.83 | 0.00% |
| 16 | BUUU Group LimitedBUUU | $4.13 | -7.94% | 8.95K | $979.99M | $0.61 - $8.10 | 0.00% |
| 17 | Avita Medical, Inc.RCEL | $17.50 | +0.99% | 375 | $549.73M | $3.22 - $18.43 | 0.00% |
| 18 | Spyre Therapeutics, Inc.SYRE | $106.16 | -0.63% | 2.23K | $10.08B | $22.13 - $110.90 | 0.00% |
| 19 | PACS Group, Inc.PACS | $50.52 | +1.02% | 625 | $8.02B | $10.31 - $51.68 | 0.01% |
| 20 | Fossil Group, Inc.FOSL | $9.88 | -0.88% | 2.76K | $583.99M | $1.70 - $10.55 | 0.00% |
| 21 | Anterix Inc.ATEX | $77.51 | +1.19% | 345 | $1.52B | $17.90 - $113.00 | 0.00% |
| 22 | AXT Inc.AXTI | $43.46 | -4.65% | 720.24K | $2.85B | $8.44 - $143.16 | 0.00% |
| 23 | Veradermics, IncorporatedMANE | $148.97 | -4.20% | 9.59K | $6.01B | $32.00 - $156.63 | 0.00% |
| 24 | Eton Pharmaceutcials, Inc.ETON | $68.91 | -0.09% | 864 | $1.99B | $14.27 - $70.64 | 0.00% |
| 25 | Oruka Therapeutics, Inc.ORKA | $109.33 | +2.08% | 10 | $7.24B | $25.23 - $115.52 | 0.00% |
| 26 | Q32 Bio Inc.QTTB | $9.32 | +0.63% | 1.01K | $279.04M | $1.91 - $23.57 | 0.00% |
| 27 | MindForge Inc.MF | $16.12 | -4.15% | 1.98K | $91.25M | $3.80 - $25.90 | 0.00% |
| 28 | Pulse Biosciences, Inc.PLSE | $57.20 | +0.25% | 11 | $4.21B | $12.56 - $61.42 | 0.00% |
| 29 | Ampco-Pittsburgh Corp.AP | $7.28 | -0.61% | 56 | $150.39M | $1.91 - $12.81 | 0.00% |
| 30 | AN2 Therapeutics, Inc.ANTX | $4.46 | +3.00% | 184.69K | $168.15M | $1.00 - $7.19 | 0.00% |
| 31 | MaxLinear, Inc.MXL | $55.85 | -4.13% | 65.58K | $5.08B | $12.77 - $128.30 | 0.00% |
| 32 | Twist Bioscience CorporationTWST | $114.58 | -7.31% | 214.57K | $7.18B | $23.30 - $219.71 | 0.00% |
| 33 | Alpha Tau Medical Ltd.DRTS | $14.24 | +1.34% | 702 | $1.29B | $3.43 - $15.79 | 0.00% |
| 34 | 10x Genomics, Inc.TXG | $59.59 | -4.15% | 10.29K | $7.16B | $15.12 - $102.81 | 0.00% |
| 35 | RF Acquisition Corp IIRFAI | $38.25 | +4.16% | 306 | $134.36M | $8.94 - $73.00 | 0.00% |
| 36 | Nuvectis Pharma, Inc.NVCT | $21.02 | +0.16% | 0 | $722.68M | $5.77 - $29.27 | 0.00% |
| 37 | Tango Therapeutics, Inc.TNGX | $25.72 | 0.00% | 2.59K | $4.34B | $7.49 - $34.39 | 0.00% |
| 38 | Bandwidth Inc.BAND | $47.53 | -1.20% | 8 | $1.45B | $12.50 - $79.08 | 0.00% |
| 39 | Entravision CommunicationEVC | $9.48 | -2.71% | 26.88K | $785.90M | $2.56 - $13.74 | 0.02% |
| 40 | OmniAb, Inc.OABI | $5.07 | -1.72% | 67 | $739.66M | $1.35 - $5.45 | 0.00% |
| 41 | ImmunityBio, Inc.IBRX | $6.60 | -0.83% | 109.62K | $6.99B | $1.95 - $12.43 | 0.00% |
| 42 | Relay Therapeutics, Inc.RLAY | $19.75 | -1.25% | 1.32K | $4.36B | $6.04 - $21.27 | 0.00% |
| 43 | Sandisk CorporationSNDK | $904.08 | -4.84% | 834.24K | $126.14B | $183.00 - $2,354.39 | 0.00% |
| 44 | Iovance Biotherapeutics, Inc.IOVA | $8.05 | -0.36% | 23.01K | $3.65B | $2.08 - $15.37 | 0.00% |
| 45 | SAIHEAT LimitedSAIH | $22.05 | 0.00% | 4 | $26.36M | $5.90 - $33.00 | 0.00% |
| 46 | Micron Technology, Inc.MU | $768.64 | -2.58% | 1.11M | $869.66B | $192.59 - $1,255.00 | 0.00% |
| 47 | Butterfly Network, Inc.BFLY | $7.08 | -1.96% | 8.39K | $1.74B | $1.90 - $10.21 | 0.00% |
| 48 | Century Therapeutics, Inc.IPSC | $1.74 | +0.17% | 0 | $315.07M | $0.43 - $3.04 | 0.00% |
| 49 | Syntec Optics Holdings, Inc.OPTX | $6.59 | -0.77% | 20.68K | $265.61M | $1.18 - $14.92 | 0.00% |
| 50 | American Well CorporationAMWL | $12.43 | 0.00% | 19 | $193.57M | $3.71 - $15.16 | 0.00% |
Trade U.S. stocks Your Way on MEXC
| RealStocks | Tokenized Stocks | Stock Futures | |
|---|---|---|---|
| What it is | RealStocks — real shares of U.S.-listed companies | Blockchain-based tokens linked to U.S. stocks/ETFs | USDT-margined futures on U.S. stock price movements |
| Ownership | Yes — actual shares | No — synthetic exposure only | No — derivative exposure only |
| Shareholder rights | Yes (e.g. dividends) | No | No |
| Trading hours | U.S. market sessions (pre-market, regular, after-hours, overnight) | 24/7 | Up to 24/7 (supported pairs) |
| Position types | Buy and hold | Buy and hold | Long, short, leveraged |
| Best for | Long-term investors seeking ownership and dividend income | Traders wanting round-the-clock access to stock exposure without holding shares | Active/short-term traders looking to speculate or hedge with leverage |
RealStocks
Tokenized Stocks
Stock FuturesWhy Trade U.S. stocks on MEXC?
RealStocks, Real Ownership
Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.
.b39e813829fa.png)
7,000+ U.S. stocks & ETFs
Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.
.b39e815d234d.png)
Seamless USDT-to-Stock Access
Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.
.b39e81c62f33.png)
.b39e81f7d220.png)
Lower-Cost Stock Trading
Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.
Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Eloxx Pharmaceuticals, Inc. (ELOX) currently leads with a 52-week gain of 1,228,445.45% as of 2026-11-12 13:12 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
Apple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBV
Apple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGBroadcom Inc.AVGOBerkshire Hathaway Inc.BRK.AVISA Inc.VABBVIE INC.ABBV
Nvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COST
Nvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COSTNvidia Corp.NVDAAmazon.Com Inc.AMZNTesla, Inc.TSLAWalmart Inc.WMTJohnson & JohnsonJNJCostco Wholesale Corp.COST
Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKOMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKOMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKOMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKO
Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKOMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKOMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKOMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXEli Lilly & Co.LLYAdvanced Micro DevicesAMDExxon Mobil CorporationXOMCoca-Cola CompanyKO
Alphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVXAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVXAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVXAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVX
Alphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVXAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVXAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVXAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMAChevron CorporationCVX
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.