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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 380 are advancing while 4,711 are declining, suggesting a mixed market tone.

Dow Jones
52,486.49
Change
+254.6+0.49%
S&P 500
7,619.38
Change
+98.45+1.31%
Nasdaq Composite
25,466.189
Change
+400.315+1.60%
24H Gainers
380
24H Losers
4,711

52 Week Gainers

#Stock52 Week Range
4601Tevogen Inc.TVGN$5.480.00%0$86.24M$3.64 - $24.910.00%
4602NervGen Pharma Corp.NGEN$1.40+2.78%301.44K$113.21M$1.28 - $6.300.00%
4603Aclarion, Inc.ACON$1.62-1.82%222$4.67M$1.54 - $9.360.00%
4604LanzaTech Global, Inc.LNZA$4.220.00%10$55.30M$4.10 - $44.000.00%
4605PowerCompute, Inc.PWCM$0.510.00%15.19K$1.30M$0.43 - $2.550.00%
4606SS Innovations International Inc.SSII$1.58+4.50%5.53K$316.21M$1.44 - $6.930.00%
4607ZeroStack Corp.ZSTK$2.75+1.89%11.38K$60.01M$1.32 - $15.040.00%
4608Processa Pharmaceuticals, Inc.PCSA$1.900.00%1.23K$5.32M$1.04 - $8.880.00%
4609aTyr Pharma, Inc.ATYR$6.74-0.01%88$19.32M$4.07 - $44.400.00%
4610Quantum Biopharma LtdQNTM$1.94-1.27%213$7.40M$1.91 - $12.420.00%
4611MIND Technology, Inc.MIND$3.15-0.25%123$28.62M$3.01 - $14.500.00%
4612Enveric Biosciences, Inc.ENVB$1.39-5.44%6$6.22M$1.17 - $13.250.00%
4613Surf Air Mobility Inc.SRFM$0.68-2.54%119.92K$92.35M$0.46 - $3.500.00%
4614CollPlant Biotechnologies LtdCLGN$4.37+10.73%11.13K$8.27M$2.64 - $22.500.00%
4615BioHarvest Sciences Inc.BHST$1.82+6.05%483$29.96M$1.37 - $8.300.00%
4616Natural Health Trends Corp.NHTC$0.83+2.97%6.12K$7.07M$0.70 - $4.000.59%
4617Lexaria Bioscience Corp.LEXX$3.93-12.46%52$8.28M$2.43 - $21.600.00%
4618Cerenome, Inc.CNSY$0.81-1.71%15.50K$6.12M$0.43 - $4.250.00%
4619BitGo Holdings, Inc.BTGO$4.23-2.75%8.83K$599.48M$4.14 - $24.500.00%
4620Filana Therapeutics, Inc.FLNA$0.48-2.65%5.22K$24.03M$0.43 - $2.270.00%
4621Kestrel Group, Ltd.KG$3.83-1.77%0$35.82M$3.74 - $17.440.00%
4622Full House Resorts, Inc.FLL$0.59-0.17%21$21.40M$0.57 - $3.370.00%
4623Pasqal Holding SAPSQL$4.34-5.92%62.26K$938.34M$4.11 - $24.690.00%
4624Nakamoto Inc.NAKA$6.08-2.88%4.44K$111.55M$3.33 - $29.340.00%
4625GT Biopharma Inc.GTBP$4.10+3.20%12$8.45M$3.83 - $28.750.03%
4626Tonix Pharmaceuticals Holding Corp.TNXP$3.98+1.92%8.76K$68.26M$3.78 - $20.560.00%
4627DocGo Inc.DCGO$0.24+2.10%5$24.04M$0.21 - $1.110.00%
4628Xanadu Quantum Technologies LimitedXNDU$2.57-0.23%161.77K$876.65M$2.34 - $42.440.00%
4629RenX Enterprises Corp.RENX$1.13-9.58%82$3.93M$0.84 - $7.000.00%
4630Oklo Inc.OKLO$24.77-3.33%236.34K$4.61B$18.54 - $116.980.00%
4631Locafy LimitedLCFY$0.88+1.00%8.14K$1.98M$0.85 - $6.200.00%
4632Prairie Operating CoPROP$0.38+2.68%771$43.20M$0.32 - $2.550.00%
4633Aurelion Inc.AURE$1.03-1.06%570$19.91M$0.85 - $5.480.00%
4634Atlas Critical Minerals CorporationATCX$1.96+7.16%0$8.66M$1.83 - $14.010.00%
4635Dermata Therapeutics, Inc.DRMA$0.69-0.72%668$3.40M$0.60 - $4.660.00%
4636enGene Therapeutics Inc.ENGN$1.91+4.10%656.77K$127.73M$1.40 - $12.250.00%
4637Teads Holding CoTEAD$0.180.00%167$17.46M$0.16 - $1.420.00%
4638York Space Systems Inc.YSS$7.35+1.52%11.75K$976.61M$5.26 - $44.540.00%
4639Byrna Technologies, Inc.BYRN$3.94-6.97%233$92.10M$3.17 - $20.690.00%
4640SL Science Holding LimitedSLBT$0.73-2.28%3.38K$548.65M$0.62 - $14.500.00%
4641ASP Isotopes Inc.ASPI$1.94-1.53%47.21K$296.65M$1.66 - $9.190.00%
4642Lucid Group, Inc.LCID$3.60-0.41%161.72K$1.42B$2.37 - $16.820.00%
4643enCore Energy Corp.EU$0.58-2.68%79.23K$113.55M$0.56 - $3.670.00%
4644Lightbridge Corp.LTBR$4.36-2.90%3.38K$163.13M$3.91 - $20.850.00%
4645Eightco Holdings Inc.ORBS$0.72-1.10%22.04K$302.81M$0.57 - $3.670.00%
4646Smartbird, Inc.BIRD$1.27+2.00%12.34K$11.87M$1.21 - $24.310.00%
4647Imunon, Inc.IMNN$0.85+13.05%1.28M$4.76M$0.57 - $4.380.00%
4648BridgeBio Oncology Therapeutics, Inc.BBOT$2.71+7.98%3.08K$184.40M$1.98 - $14.870.00%
4649DNA X, Inc.SONM$2.35+0.21%10.89K$3.50M$2.02 - $11.160.00%
4650Acurx Pharmaceuticals, Inc.ACXP$1.06+0.95%9.34K$5.92M$0.95 - $7.540.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Tevogen Inc. (TVGN) currently leads with a 52-week gain of 76.47% as of 2026-11-12 14:03 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.