52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview
U.S. stocks are mixed today. The Dow Jones is +0.49%, the S&P 500 is +1.31%, and the Nasdaq Composite is +1.60%. Across individual stocks, 380 are advancing while 4,711 are declining, suggesting a mixed market tone.
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 4601 | Tevogen Inc.TVGN | $5.48 | 0.00% | 0 | $86.24M | $3.64 - $24.91 | 0.00% |
| 4602 | NervGen Pharma Corp.NGEN | $1.40 | +2.78% | 301.44K | $113.21M | $1.28 - $6.30 | 0.00% |
| 4603 | Aclarion, Inc.ACON | $1.62 | -1.82% | 222 | $4.67M | $1.54 - $9.36 | 0.00% |
| 4604 | LanzaTech Global, Inc.LNZA | $4.22 | 0.00% | 10 | $55.30M | $4.10 - $44.00 | 0.00% |
| 4605 | PowerCompute, Inc.PWCM | $0.51 | 0.00% | 15.19K | $1.30M | $0.43 - $2.55 | 0.00% |
| 4606 | SS Innovations International Inc.SSII | $1.58 | +4.50% | 5.53K | $316.21M | $1.44 - $6.93 | 0.00% |
| 4607 | ZeroStack Corp.ZSTK | $2.75 | +1.89% | 11.38K | $60.01M | $1.32 - $15.04 | 0.00% |
| 4608 | Processa Pharmaceuticals, Inc.PCSA | $1.90 | 0.00% | 1.23K | $5.32M | $1.04 - $8.88 | 0.00% |
| 4609 | aTyr Pharma, Inc.ATYR | $6.74 | -0.01% | 88 | $19.32M | $4.07 - $44.40 | 0.00% |
| 4610 | Quantum Biopharma LtdQNTM | $1.94 | -1.27% | 213 | $7.40M | $1.91 - $12.42 | 0.00% |
| 4611 | MIND Technology, Inc.MIND | $3.15 | -0.25% | 123 | $28.62M | $3.01 - $14.50 | 0.00% |
| 4612 | Enveric Biosciences, Inc.ENVB | $1.39 | -5.44% | 6 | $6.22M | $1.17 - $13.25 | 0.00% |
| 4613 | Surf Air Mobility Inc.SRFM | $0.68 | -2.54% | 119.92K | $92.35M | $0.46 - $3.50 | 0.00% |
| 4614 | CollPlant Biotechnologies LtdCLGN | $4.37 | +10.73% | 11.13K | $8.27M | $2.64 - $22.50 | 0.00% |
| 4615 | BioHarvest Sciences Inc.BHST | $1.82 | +6.05% | 483 | $29.96M | $1.37 - $8.30 | 0.00% |
| 4616 | Natural Health Trends Corp.NHTC | $0.83 | +2.97% | 6.12K | $7.07M | $0.70 - $4.00 | 0.59% |
| 4617 | Lexaria Bioscience Corp.LEXX | $3.93 | -12.46% | 52 | $8.28M | $2.43 - $21.60 | 0.00% |
| 4618 | Cerenome, Inc.CNSY | $0.81 | -1.71% | 15.50K | $6.12M | $0.43 - $4.25 | 0.00% |
| 4619 | BitGo Holdings, Inc.BTGO | $4.23 | -2.75% | 8.83K | $599.48M | $4.14 - $24.50 | 0.00% |
| 4620 | Filana Therapeutics, Inc.FLNA | $0.48 | -2.65% | 5.22K | $24.03M | $0.43 - $2.27 | 0.00% |
| 4621 | Kestrel Group, Ltd.KG | $3.83 | -1.77% | 0 | $35.82M | $3.74 - $17.44 | 0.00% |
| 4622 | Full House Resorts, Inc.FLL | $0.59 | -0.17% | 21 | $21.40M | $0.57 - $3.37 | 0.00% |
| 4623 | Pasqal Holding SAPSQL | $4.34 | -5.92% | 62.26K | $938.34M | $4.11 - $24.69 | 0.00% |
| 4624 | Nakamoto Inc.NAKA | $6.08 | -2.88% | 4.44K | $111.55M | $3.33 - $29.34 | 0.00% |
| 4625 | GT Biopharma Inc.GTBP | $4.10 | +3.20% | 12 | $8.45M | $3.83 - $28.75 | 0.03% |
| 4626 | Tonix Pharmaceuticals Holding Corp.TNXP | $3.98 | +1.92% | 8.76K | $68.26M | $3.78 - $20.56 | 0.00% |
| 4627 | DocGo Inc.DCGO | $0.24 | +2.10% | 5 | $24.04M | $0.21 - $1.11 | 0.00% |
| 4628 | Xanadu Quantum Technologies LimitedXNDU | $2.57 | -0.23% | 161.77K | $876.65M | $2.34 - $42.44 | 0.00% |
| 4629 | RenX Enterprises Corp.RENX | $1.13 | -9.58% | 82 | $3.93M | $0.84 - $7.00 | 0.00% |
| 4630 | Oklo Inc.OKLO | $24.77 | -3.33% | 236.34K | $4.61B | $18.54 - $116.98 | 0.00% |
| 4631 | Locafy LimitedLCFY | $0.88 | +1.00% | 8.14K | $1.98M | $0.85 - $6.20 | 0.00% |
| 4632 | Prairie Operating CoPROP | $0.38 | +2.68% | 771 | $43.20M | $0.32 - $2.55 | 0.00% |
| 4633 | Aurelion Inc.AURE | $1.03 | -1.06% | 570 | $19.91M | $0.85 - $5.48 | 0.00% |
| 4634 | Atlas Critical Minerals CorporationATCX | $1.96 | +7.16% | 0 | $8.66M | $1.83 - $14.01 | 0.00% |
| 4635 | Dermata Therapeutics, Inc.DRMA | $0.69 | -0.72% | 668 | $3.40M | $0.60 - $4.66 | 0.00% |
| 4636 | enGene Therapeutics Inc.ENGN | $1.91 | +4.10% | 656.77K | $127.73M | $1.40 - $12.25 | 0.00% |
| 4637 | Teads Holding CoTEAD | $0.18 | 0.00% | 167 | $17.46M | $0.16 - $1.42 | 0.00% |
| 4638 | York Space Systems Inc.YSS | $7.35 | +1.52% | 11.75K | $976.61M | $5.26 - $44.54 | 0.00% |
| 4639 | Byrna Technologies, Inc.BYRN | $3.94 | -6.97% | 233 | $92.10M | $3.17 - $20.69 | 0.00% |
| 4640 | SL Science Holding LimitedSLBT | $0.73 | -2.28% | 3.38K | $548.65M | $0.62 - $14.50 | 0.00% |
| 4641 | ASP Isotopes Inc.ASPI | $1.94 | -1.53% | 47.21K | $296.65M | $1.66 - $9.19 | 0.00% |
| 4642 | Lucid Group, Inc.LCID | $3.60 | -0.41% | 161.72K | $1.42B | $2.37 - $16.82 | 0.00% |
| 4643 | enCore Energy Corp.EU | $0.58 | -2.68% | 79.23K | $113.55M | $0.56 - $3.67 | 0.00% |
| 4644 | Lightbridge Corp.LTBR | $4.36 | -2.90% | 3.38K | $163.13M | $3.91 - $20.85 | 0.00% |
| 4645 | Eightco Holdings Inc.ORBS | $0.72 | -1.10% | 22.04K | $302.81M | $0.57 - $3.67 | 0.00% |
| 4646 | Smartbird, Inc.BIRD | $1.27 | +2.00% | 12.34K | $11.87M | $1.21 - $24.31 | 0.00% |
| 4647 | Imunon, Inc.IMNN | $0.85 | +13.05% | 1.28M | $4.76M | $0.57 - $4.38 | 0.00% |
| 4648 | BridgeBio Oncology Therapeutics, Inc.BBOT | $2.71 | +7.98% | 3.08K | $184.40M | $1.98 - $14.87 | 0.00% |
| 4649 | DNA X, Inc.SONM | $2.35 | +0.21% | 10.89K | $3.50M | $2.02 - $11.16 | 0.00% |
| 4650 | Acurx Pharmaceuticals, Inc.ACXP | $1.06 | +0.95% | 9.34K | $5.92M | $0.95 - $7.54 | 0.00% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
How is the 52-week gain calculated?
Which stock has gained the most over 52 weeks?
Why use a 52-week stock performance ranking?
Does strong 52-week performance guarantee future gains?
How is this different from the daily Top Gainers list?
Discover Top US Stocks
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.








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