52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 289 are advancing while 4,801 are declining, suggesting a mixed market tone.

Dow Jones

52,486.49

Change

+254.6+0.49%

S&P 500

7,619.38

Change

+98.45+1.31%

Nasdaq Composite

25,466.189

Change

+400.315+1.60%

24H Gainers

289

24H Losers

4,801

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
4651	AI Financial CorporationAIFC	$0.18	-2.66%	36.53K	$25.59M	$0.16 - $1.08	0.00%
4652	Rocket One Inc.RKTO	$0.36	-2.70%	12.83K	$8.99M	$0.33 - $2.45	0.00%
4653	Exascale Labs Holdings Inc.XLAB	$1.09	+4.40%	68.82K	$72.05M	$0.78 - $7.39	0.00%
4654	Globavend Holdings LimitedGVH	$0.94	+4.20%	3.79K	$4.06M	$0.77 - $6.46	0.00%
4655	Vistance Networks, Inc.VISN	$4.03	-0.35%	424	$929.42M	$3.90 - $19.95	1.38%
4656	Creative Medical Technology Holdings, Inc.CELZ	$0.63	0.00%	3.41K	$4.15M	$0.59 - $4.72	0.00%
4657	Aptera Motors Corp.SEV	$1.56	-0.89%	955	$93.33M	$1.29 - $8.30	0.00%
4658	TEN Holdings, Inc.XHLD	$0.85	+0.12%	20.83K	$10.50M	$0.38 - $15.43	0.00%
4659	Tilray Brands, Inc.TLRY	$2.58	-1.00%	43.29K	$381.29M	$2.48 - $15.70	0.00%
4660	Shuttle Pharmaceuticals Holdings, Inc.SHPH	$5.26	-2.77%	12.83K	$25.09M	$2.58 - $44.40	0.00%
4661	Defi Technologies, Inc.DEFT	$0.34	+1.52%	9.81K	$130.09M	$0.30 - $1.73	0.00%
4662	Dogwood Therapeutics, Inc.DWTX	$1.22	+4.64%	3.56K	$46.60M	$0.90 - $7.04	0.00%
4663	PureCycle Technologies, Inc.PCT	$2.00	-1.76%	5.74K	$403.01M	$1.59 - $14.20	0.00%
4664	Xtend AI Robotics, Inc.XTND	$1.29	-3.05%	10.26K	$286.50M	$0.80 - $7.15	0.00%
4665	Maris-Tech Ltd.MTEK	$0.27	+4.62%	348.03K	$2.64M	$0.21 - $2.82	0.00%
4666	Antalpha Platform Holding CompanyANTA	$2.03	-1.07%	2.59K	$38.66M	$1.50 - $11.19	0.00%
4667	DirectBooking Technology Co., LtdZDAI	$1.31	-15.02%	12	$10.49M	$1.10 - $12.00	0.00%
4668	Rail Vision Ltd.RVSN	$2.32	-1.82%	940	$5.09M	$2.32 - $12.58	0.00%
4669	Avax One Technology LtdAVX	$4.51	-3.01%	216	$33.39M	$2.81 - $31.80	0.00%
4670	The Generation Essentials GroupTGE	$0.26	-5.59%	33.67K	$17.45M	$0.22 - $1.90	0.00%
4671	Pulsenmore Ltd.PLSM	$1.51	+1.41%	612	$10.21M	$1.42 - $12.97	0.00%
4672	Sow Good Inc.SOWG	$1.98	-1.59%	3.21K	$39.76M	$1.04 - $15.90	0.00%
4673	Loop Industries, Inc.LOOP	$0.26	+7.56%	530	$12.50M	$0.23 - $1.54	0.00%
4674	Guardforce AI Co., LimitedGFAI	$0.18	0.00%	1.55K	$5.75M	$0.17 - $0.98	0.00%
4675	Upexi, Inc.UPXI	$0.68	+0.01%	119.11K	$59.96M	$0.54 - $3.65	0.00%
4676	Intelligent Group LimitedINTJ	$2.36	+12.12%	11.39K	$4.92M	$1.69 - $12.52	0.00%
4677	Research Frontiers Inc.REFR	$0.36	0.00%	160	$12.55M	$0.33 - $2.10	0.00%
4678	Gemini Space Station, Inc.GEMI	$2.73	+1.11%	36.67K	$356.41M	$2.31 - $15.27	0.00%
4679	SANGRIX INC.SGRX	$0.41	+3.25%	40.18K	$1.63M	$0.30 - $3.44	0.00%
4680	OSR Health, Inc.OSRH	$0.12	-53.28%	22.28M	$0	$0.07 - $0.90	0.00%
4681	NeuroOne Medical Technologies CorporationNMTC	$0.86	+9.91%	310	$7.88M	$0.75 - $6.12	0.00%
4682	Psyence Biomedical LtdPBM	$3.13	-0.13%	443	$11.94M	$1.92 - $18.62	0.00%
4683	BOXABL, Inc.BXBL	$1.92	-0.93%	407	$451.71M	$1.76 - $11.99	0.00%
4684	NuScale Power CorporationSMR	$5.05	-3.44%	266.03K	$2.07B	$4.28 - $27.78	0.00%
4685	Imunon, Inc.IMNN	$0.77	+2.00%	1.26M	$4.30M	$0.57 - $4.38	0.00%
4686	LASE Corp.LASE	$0.62	-5.52%	87.44K	$30.90M	$0.38 - $4.49	0.00%
4687	Australian Oilseeds Holdings LimitedCOOT	$0.25	-6.99%	9.28K	$12.36M	$0.25 - $1.33	0.00%
4688	Armlogi Holding Corp.BTOC	$1.78	0.00%	102	$5.07M	$1.74 - $11.49	0.00%
4689	Alset Inc.AEI	$0.51	-2.86%	6.57K	$19.80M	$0.47 - $3.98	0.00%
4690	Bone Biologics Corp.BBLG	$0.34	-3.95%	6.27K	$1.15M	$0.32 - $2.39	0.00%
4691	Odyssey Marine Exploration, Inc.OMEX	$10.13	-3.84%	16	$23.77M	$9.59 - $66.75	0.00%
4692	MetaVia Inc.MTVA	$1.48	+2.50%	4.86K	$7.63M	$0.97 - $13.42	0.00%
4693	Freightos LimitedCRGO	$0.78	+3.06%	495	$40.85M	$0.58 - $4.24	0.00%
4694	Cheer Holding, Inc.CHR	$1.30	-2.03%	402	$2.40M	$1.15 - $9.49	0.00%
4695	Aqua Metals, Inc.AQMS	$1.43	+0.42%	206	$5.10M	$1.02 - $8.39	0.00%
4696	Galaxy Payroll Group LimitedGLXG	$0.73	+4.86%	50	$4.61M	$0.53 - $4.79	0.00%
4697	Terrestrial Energy Inc.IMSR	$2.49	-1.58%	11.07K	$317.97M	$2.43 - $14.28	0.00%
4698	Ensysce Biosciences, Inc.ENSC	$0.38	+5.26%	44.92K	$7.39M	$0.23 - $2.17	0.00%
4699	The OLB Group, Inc.OLB	$0.19	0.00%	23.13K	$5.90M	$0.16 - $1.80	0.00%
4700	Fusemachines Inc.FUSE	$0.34	+1.52%	29	$11.72M	$0.22 - $3.67	0.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

AI Financial Corporation (AIFC) currently leads with a 52-week gain of 78.70% as of 2026-11-12 13:59 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

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Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.