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52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 376 are advancing while 4,714 are declining, suggesting a mixed market tone.

Dow Jones
52,486.49
Change
+254.6+0.49%
S&P 500
7,619.38
Change
+98.45+1.31%
Nasdaq Composite
25,466.189
Change
+400.315+1.60%
24H Gainers
376
24H Losers
4,714

52 Week Losers

#Stock52 Week Range
401PRF Technologies Ltd.PRFX$0.730.00%5.34K$2.23M$0.64 - $7.950.00%
402Arbor Realty Trust, Inc.ABR$1.40+0.72%8.42K$258.03M$1.39 - $9.340.93%
403Mercer International Inc.MERC$0.26+6.97%12.05M$17.28M$0.12 - $2.850.00%
404Vivid Seats Inc.SEAT$1.45+1.83%3$16.27M$1.34 - $10.270.00%
405OIO GroupOIO$1.77+1.12%103.87K$616.00M$1.36 - $11.550.00%
406QumulusAI, Inc.QMLS$3.29+2.65%1.63K$104.73M$2.58 - $38.000.00%
407Anavex Life SciencesAVXL$1.06-2.30%3.43K$98.35M$1.05 - $7.250.00%
408WiMi Hologram Cloud Inc.WIMI$0.480.00%3$8.36M$0.44 - $3.260.00%
409Lyra Therapeutics, Inc.LYRA$0.000.00%0$0$0.00 - $4.800.00%
410Bonk, Inc.BNKK$1.02+3.88%1.52K$8.09M$0.90 - $8.900.00%
411TScan Therapeutics, Inc.TCRX$0.180.00%146$11.68M$0.17 - $1.470.00%
412TransCode Therapeutics, Inc.RNAZ$1.36+2.63%11.75K$23.11M$1.33 - $12.600.00%
413Nyxoah SANYXH$0.92+2.12%1.25K$91.05M$0.80 - $5.920.00%
414MBody AI Ltd.MBAI$2.04-6.61%34$31.14M$1.61 - $27.440.00%
415DEFSEC Technologies Inc.DFSC$0.51-4.72%2.81K$2.32M$0.49 - $5.090.00%
416Organogenesis Holdings Inc.ORGO$1.02-5.54%1.71K$131.76M$0.73 - $6.560.00%
417Hadron Energy, Inc.HDRN$0.64-3.62%645$45.69M$0.60 - $5.400.00%
418BeneficientBENF$0.68-3.00%2.12K$12.85M$0.50 - $9.960.00%
419Neumora Therapeutics, Inc.NMRA$0.46+1.11%10.15K$85.87M$0.32 - $3.650.00%
420Revelation Biosciences, Inc.REVB$4.40+7.93%149$2.34M$3.08 - $40.600.00%
421Barfresh Food Group Inc.BRFH$0.49-1.60%11.22K$8.04M$0.42 - $3.500.00%
422Amesite Inc.AMST$0.47-4.85%758$3.08M$0.46 - $3.050.00%
423LENZ Therapeutics, Inc.LENZ$4.16+0.36%592$130.84M$2.80 - $32.130.00%
424Thryv Holdings, Inc.THRY$1.03+7.89%628$45.59M$0.90 - $6.390.00%
425IQSTEL INC.IQST$0.790.00%1.45K$8.63M$0.73 - $5.170.00%
426Corteva, Inc.CTVA$10.90-10.13%281.25K$7.27B$10.89 - $90.970.06%
427Greenland Mines LtdGRML$3.84-2.59%15.25K$52.55M$2.82 - $27.480.00%
428Change Agents CorporationCHGA$0.89+0.91%115$995.87K$0.69 - $5.740.00%
429Greenland Energy CompanyGLND$2.13-0.47%19.58K$101.45M$1.09 - $23.000.00%
430Z Squared Inc.ZSQR$2.50-2.50%3.30K$132.55M$2.11 - $18.800.00%
431Anebulo Pharmaceuticals, Inc.ANEB$0.000.00%0$0$0.00 - $2.490.00%
432Dominari Holdings Inc.DOMH$0.90+1.01%15$21.82M$0.70 - $5.711.16%
433loanDepot, Inc.LDI$0.48+1.98%29.89K$112.38M$0.45 - $3.240.00%
434BioNexus Gene Lab Corp.BGLC$0.81-8.93%1.03K$2.36M$0.80 - $5.130.00%
435Presidio Property Trust, Inc.SQFT$0.85-6.48%1.26K$1.22M$0.72 - $5.181.09%
436Compass Therapeutics, Inc.CMPX$0.82+1.61%2.38K$147.67M$0.67 - $6.880.00%
437Expion Energy, Inc.XPON$2.550.00%51$2.58M$2.26 - $19.200.00%
438FuboTV Inc.FUBO$7.90+1.02%294$238.61M$7.44 - $47.400.00%
439Ucommune International LtdUK$1.48-4.15%516$985.70K$1.39 - $10.500.00%
440ZenaTech, Inc.ZENA$0.70+0.43%16.08K$140.61M$0.58 - $5.170.00%
441Scienture Holdings, Inc.SCNX$3.040.00%46$5.37M$2.64 - $19.470.00%
442American Vanguard CorporationAVD$0.87-0.02%204$25.55M$0.81 - $5.550.00%
443Caribou Biosciences, Inc.CRBU$0.39-0.76%3.61K$42.13M$0.36 - $2.490.00%
444SunCar Technology Group Inc.SDA$0.32-0.31%199.41K$19.13M$0.13 - $2.450.00%
445Elicio Therapeutics, Inc.ELTX$1.59-1.12%0$45.01M$1.25 - $16.000.00%
446Upland Software, Inc.UPLD$3.06-2.86%119$8.69M$2.75 - $19.600.00%
447Beyond Meat, Inc.BYND$5.81-0.48%8.99K$99.95M$5.51 - $44.400.00%
448Conexeu Sciences Inc.CNXU$2.27-3.16%60$71.84M$2.01 - $18.790.00%
449CISO Global, Inc.CISO$0.17-1.69%944$7.93M$0.15 - $1.010.00%
450Anbio BiotechnologyNNNN$3.93-2.65%14$179.08M$3.09 - $44.730.00%

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Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
PRF Technologies Ltd. (PRFX) currently shows a 52-week decline of 84.87% as of 2026-11-12 13:39 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.