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52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 381 are advancing while 4,709 are declining, suggesting a mixed market tone.

Dow Jones
52,486.49
Change
+254.6+0.49%
S&P 500
7,619.38
Change
+98.45+1.31%
Nasdaq Composite
25,466.189
Change
+400.315+1.60%
24H Gainers
381
24H Losers
4,709

52 Week Losers

#Stock52 Week Range
5101Cumberland Pharmaceuticals Inc.CPIX$6.05-1.87%545$90.66M$1.85 - $9.280.00%
5102Able View Global Inc.ABLV$2.25-2.30%59$55.19M$0.54 - $2.960.00%
5103Lindblad Expeditions Holdings Inc.LIND$34.92-1.33%509.26K$2.29B$11.37 - $38.850.00%
5104Vera Bradley, Inc.VRA$7.76-1.65%245$222.62M$1.39 - $8.360.00%
5105American Outdoor Brands, Inc.AOUT$19.050.00%68$240.43M$6.26 - $19.500.00%
5106Hinge Health, Inc.HNGE$122.05-0.06%1.47K$9.86B$30.08 - $126.400.00%
5107Vestis CorporationVSTS$15.65+9.13%28$2.07B$5.00 - $16.900.00%
5108EuroDry LtdEDRY$39.340.00%69$112.77M$12.30 - $73.070.00%
5109AbCellera Biologics Inc.ABCL$11.64-2.90%53.90K$3.57B$2.75 - $15.020.00%
5110LB Pharmaceuticals Inc.LBRX$44.690.00%60$1.46B$14.40 - $50.160.00%
5111Tilly's Inc.TLYS$4.15-2.79%23$96.64M$1.14 - $6.250.00%
5112Syntec Optics Holdings, Inc.OPTX$6.49-2.27%32.45K$261.58M$1.18 - $14.920.00%
5113American Well CorporationAMWL$12.430.00%19$193.57M$3.71 - $15.160.00%
5114Century Therapeutics, Inc.IPSC$1.74+0.17%0$315.07M$0.43 - $3.040.00%
5115Butterfly Network, Inc.BFLY$7.01-1.68%10.47K$1.72B$1.90 - $10.210.00%
5116Iovance Biotherapeutics, Inc.IOVA$7.96-1.55%38.32K$3.60B$2.08 - $15.370.00%
5117Relay Therapeutics, Inc.RLAY$19.39-3.05%1.38K$4.28B$6.04 - $21.270.00%
5118SAIHEAT LimitedSAIH$22.050.00%4$26.36M$5.90 - $33.000.00%
5119Micron Technology, Inc.MU$771.74-5.41%1.29M$873.16B$192.59 - $1,255.000.00%
5120ImmunityBio, Inc.IBRX$6.54-1.71%130.40K$6.93B$1.95 - $12.430.00%
5121Sandisk CorporationSNDK$913.37-7.79%984.27K$126.14B$183.00 - $2,354.390.00%
5122OmniAb, Inc.OABI$5.07-1.72%67$739.66M$1.35 - $5.450.00%
5123Entravision CommunicationEVC$9.48-4.71%26.88K$785.90M$2.56 - $13.740.02%
5124Bandwidth Inc.BAND$47.53-1.20%8$1.45B$12.50 - $79.080.00%
5125Tango Therapeutics, Inc.TNGX$25.720.00%2.59K$4.34B$7.49 - $34.390.00%
5126Nuvectis Pharma, Inc.NVCT$21.02+0.16%0$722.68M$5.77 - $29.270.00%
5127RF Acquisition Corp IIRFAI$38.25+4.16%306$134.36M$8.94 - $73.000.00%
5128Alpha Tau Medical Ltd.DRTS$14.16+0.80%779$1.28B$3.43 - $15.790.00%
5129Twist Bioscience CorporationTWST$113.75-7.97%280.32K$7.13B$23.30 - $219.710.00%
513010x Genomics, Inc.TXG$60.33-2.96%10.42K$7.25B$15.12 - $102.810.00%
5131AN2 Therapeutics, Inc.ANTX$4.46+3.00%184.69K$168.15M$1.00 - $7.190.00%
5132Ampco-Pittsburgh Corp.AP$7.28-0.61%56$150.39M$1.91 - $12.810.00%
5133Pulse Biosciences, Inc.PLSE$57.20+0.25%11$4.21B$12.56 - $61.420.00%
5134MaxLinear, Inc.MXL$56.77-2.53%74.69K$5.17B$12.77 - $128.300.00%
5135MindForge Inc.MF$16.12-4.15%2.09K$91.25M$3.80 - $25.900.00%
5136Q32 Bio Inc.QTTB$9.32+0.63%1.01K$279.04M$1.91 - $23.570.00%
5137Oruka Therapeutics, Inc.ORKA$109.33+2.08%1.01K$7.24B$25.23 - $115.520.00%
5138Eton Pharmaceutcials, Inc.ETON$68.89-0.11%1.28K$1.99B$14.27 - $70.640.00%
5139Veradermics, IncorporatedMANE$149.35-4.20%9.72K$6.01B$32.00 - $156.630.00%
5140AXT Inc.AXTI$43.59-4.36%784.14K$2.86B$8.44 - $143.160.00%
5141Anterix Inc.ATEX$77.51+1.19%345$1.52B$17.90 - $113.000.00%
5142Fossil Group, Inc.FOSL$9.88-0.85%3.39K$584.17M$1.70 - $10.550.00%
5143PACS Group, Inc.PACS$50.55+1.02%627$8.02B$10.31 - $51.680.01%
5144Spyre Therapeutics, Inc.SYRE$107.05+0.21%4.89K$10.17B$22.13 - $110.900.00%
5145Avita Medical, Inc.RCEL$17.50+1.04%426$549.98M$3.22 - $18.430.00%
5146BUUU Group LimitedBUUU$4.13-7.94%8.95K$979.99M$0.61 - $8.100.00%
5147New Century Logistics (BVI) LimitedNCEW$16.72+1.06%101$53.51M$2.80 - $20.830.00%
5148Vince Holding Corp.VNCE$13.25-0.99%283$171.53M$1.95 - $13.900.00%
5149CareDx, Inc.CDNA$81.47-1.14%2.39K$4.28B$15.15 - $90.870.00%
5150Kodiak Sciences Inc.KOD$108.63-0.33%1.37K$6.83B$18.05 - $112.310.00%

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Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Cumberland Pharmaceuticals Inc. (CPIX) currently shows a 52-week decline of 182.76% as of 2026-11-12 13:31 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.