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52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 289 are advancing while 4,801 are declining, suggesting a mixed market tone.

Dow Jones
52,486.49
Change
+254.6+0.49%
S&P 500
7,619.38
Change
+98.45+1.31%
Nasdaq Composite
25,466.189
Change
+400.315+1.60%
24H Gainers
289
24H Losers
4,801

52 Week Losers

#Stock52 Week Range
5051Kiniksa Pharmaceuticals International, plcKNSA$95.87+0.21%0$4.68B$37.02 - $99.310.00%
5052Sweetgreen, Inc.SG$12.70+1.40%676$1.36B$4.49 - $13.890.00%
5053Cheesecake Factory (The)CAKE$109.280.00%137$5.45B$43.07 - $118.630.01%
5054Jerash Holdings (US), Inc.JRSH$7.800.00%242$99.06M$2.85 - $7.900.03%
5055Turn Therapeutics Inc.TTRX$10.53+7.06%51.81K$297.30M$2.57 - $16.450.00%
5056Noodles & CompanyNDLS$14.27-2.23%13.10K$85.11M$3.57 - $19.000.00%
5057Replimune Group, Inc.REPL$21.70-0.21%365$2.06B$1.50 - $23.540.00%
5058SharkNinja, Inc.SN$227.63+1.00%179$32.08B$83.21 - $232.760.00%
5059Axogen, Inc.AXGN$58.54+0.16%228$3.50B$23.00 - $59.720.00%
5060Quhuo LimitedQH$2.99-0.37%62$7.79M$0.07 - $12.810.00%
5061Oportun Financial CorporationOPRT$11.790.00%4$543.05M$4.03 - $13.340.00%
5062Maravai LifeSciences Holdings, Inc.MRVI$7.95+2.59%3.92K$1.18B$2.80 - $9.420.00%
5063Lifetime Brands, Inc.LCUT$7.97+0.06%106.95K$183.30M$3.02 - $10.170.02%
5064QTREX Quantum Ltd.QTEX$0.96-2.24%210.72K$53.78M$0.28 - $3.850.00%
5065Starz Entertainment Corp.STRZ$26.72+0.06%0$449.07M$8.40 - $32.580.00%
5066Lumentum Holdings Inc.LITE$624.87-0.95%53.06K$56.68B$215.35 - $1,143.000.00%
5067Surrozen, Inc.SRZN$32.14-1.96%131.09K$373.15M$12.12 - $37.830.00%
5068MARRIOTT VACATIONS WORLDWIDE CORPORATIONVAC$117.51-0.01%0$4.04B$44.58 - $131.340.03%
5069Trueblue, Inc.TBI$12.87+7.56%100$392.18M$3.18 - $13.590.00%
5070Enliven Therapeutics, Inc.ELVN$51.18-0.71%0$3.77B$14.79 - $62.320.00%
5071Septerna, Inc.SEPN$48.550.00%2$2.37B$18.64 - $53.340.00%
5072Globus Maritime LimitedGLBS$3.04-1.87%0$65.52M$1.14 - $4.060.00%
5073DHI Group, Inc.DHX$4.43-1.56%199.49K$188.12M$1.44 - $5.190.00%
5074Delcath Systems Inc.DCTH$21.78-0.95%62$755.74M$8.12 - $22.330.00%
5075Agencia Comercial Spirits LtdAGCC$14.09-0.02%0$601.15M$5.00 - $25.730.00%
5076Hongli Group Inc.HLP$4.36+1.14%5.79K$325.79M$0.34 - $4.870.00%
5077Dell Technologies Inc.DELL$361.60-3.24%50.41K$114.06B$110.22 - $595.510.01%
5078Prelude Therapeutics IncorporatedPRLD$3.78+0.80%249.66K$301.90M$1.29 - $6.830.00%
5079Amylyx Pharmaceuticals, Inc.AMLX$32.00+1.05%93$3.56B$10.83 - $41.140.00%
5080Forum Energy Technologies, Inc.FET$75.77+1.21%0$869.27M$28.68 - $91.990.00%
5081Elite Express Holding Inc.ETS$1.49-2.68%3.69K$69.05M$0.39 - $2.750.00%
5082Kelly Services Inc.KELYB$23.30-5.21%0$76.78M$8.38 - $125.000.01%
5083Shattuck Labs, Inc.STTK$5.040.00%21$506.33M$1.72 - $8.330.00%
5084Sezzle Inc.SEZL$150.68-2.48%464$5.09B$49.50 - $195.710.00%
5085Rackspace Technology, Inc.RXT$3.14+2.28%11.19K$800.30M$0.39 - $8.600.00%
5086Glaukos CorporationGKOS$244.74+0.14%576$14.49B$87.32 - $255.190.00%
5087Omeros CorporationOMER$18.25+0.88%532$1.32B$6.24 - $21.240.00%
5088Vestis CorporationVSTS$14.35-0.14%749.46K$1.90B$5.00 - $16.900.00%
5089Ultralife CorporationULBI$15.46-1.82%2$257.53M$4.90 - $15.830.00%
5090RINGCENTRAL, INC.RNG$75.250.00%20$5.62B$24.14 - $98.140.00%
5091Aehr Test SystemsAEHR$63.41-0.66%41.72K$2.07B$18.70 - $147.400.00%
5092Revolution Medicines, Inc.RVMD$181.20-0.45%628$39.19B$63.50 - $224.310.00%
5093First Tracks Biotherapeutics, Inc.TRAX$51.380.00%4$2.09B$14.72 - $54.780.00%
5094Xencor, Inc.XNCR$39.78-0.50%22$2.99B$10.38 - $40.600.00%
5095Maase Inc.MAAS$10.27+5.45%21.12K$4.47B$3.70 - $24.900.00%
5096TOP Financial Group LimitedTOP$15.00+2.45%90.81K$1.95B$3.06 - $17.420.00%
5097Andersen Group Inc.ANDG$65.79+0.11%349.27K$1.28B$18.12 - $68.410.00%
5098Iridium Communications Inc.IRDM$47.20+2.02%12$5.01B$15.64 - $57.180.01%
5099Rallybio CorporationRLYB$15.710.00%0$84.56M$3.67 - $17.570.00%
5100Cumberland Pharmaceuticals Inc.CPIX$6.05-1.87%104$90.66M$1.85 - $9.280.00%

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Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Kiniksa Pharmaceuticals International, plc (KNSA) currently shows a 52-week decline of 136.25% as of 2026-11-12 13:31 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.