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52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 377 are advancing while 4,713 are declining, suggesting a mixed market tone.

Dow Jones
52,486.49
Change
+254.6+0.49%
S&P 500
7,619.38
Change
+98.45+1.31%
Nasdaq Composite
25,466.189
Change
+400.315+1.60%
24H Gainers
377
24H Losers
4,713

52 Week Losers

#Stock52 Week Range
801ProMIS Neurosciences Inc.PMN$3.85+2.53%3.04K$34.57M$2.78 - $27.400.00%
802Solidion Technology, Inc.STI$4.07+1.24%2.59K$36.56M$2.94 - $46.000.00%
803Comtech TelecommunicationsCMTL$1.25-0.40%23$37.67M$1.10 - $6.210.00%
804X-Energy, Inc.XE$11.01+1.95%188.30K$3.21B$8.68 - $37.100.00%
805Sky Quarry Inc.SKYQ$1.18+0.51%39.37K$15.02M$1.10 - $19.450.00%
806Black Rock Coffee Bar, Inc.BRCB$8.72+0.65%368$246.50M$6.11 - $25.200.00%
807Cipher Digital Inc.CIFR$6.57-6.19%1.04M$3.00B$5.07 - $30.140.00%
808Everbright Digital Holding LimitedEDHL$6.41+1.25%2.71K$10.28M$2.00 - $17.490.00%
809Draganfly Inc.DPRO$2.95-1.67%8.66K$115.47M$2.68 - $10.620.00%
810Spero Therapeutics, Inc.SPRO$1.01-0.69%5.16K$58.82M$0.96 - $3.080.00%
811DeFi Development Corp.DFDV$3.17-2.13%33.42K$126.18M$2.44 - $8.710.00%
812Rigetti Computing, Inc.RGTI$10.75-2.68%716.43K$3.59B$9.19 - $31.650.00%
813Veea Inc.VEEA$4.53-0.40%4.65K$14.40M$1.34 - $16.440.00%
814Seritage Growth PropertiesSRG$1.60-3.16%164.03K$90.29M$1.53 - $4.230.06%
815UP Fintech Holding Ltd AmericanTIGR$3.96-0.13%20.18K$680.31M$3.61 - $11.350.00%
816Gyrodyne, LLCGYRO$3.650.00%0$8.04M$3.65 - $9.630.00%
817Canton Strategic Holdings, Inc.CNTN$1.89-1.56%35.98K$150.60M$1.66 - $5.260.00%
818AeroVironment, Inc.AVAV$123.65+0.90%23.69K$6.28B$100.40 - $408.250.00%
819D-Wave Quantum Inc.QBTS$10.10-4.37%290.60K$3.72B$8.48 - $32.390.00%
820ADC Therapeutics SAADCT$1.55-3.13%1.44K$197.88M$0.78 - $4.980.00%
821Obsidian Therapeutics, Inc.OBX$13.050.00%490$846.91M$9.60 - $49.970.00%
822Lucky Strike Entertainment CorporationLUCK$3.230.00%14$260.61M$3.20 - $9.590.08%
823Energys Group LimitedENGS$0.51-13.12%1.41M$27.63M$0.45 - $5.000.00%
824Sol Strategies Inc.STKE$1.16+0.09%13.04K$31.98M$0.85 - $3.120.00%
825Gloo Holdings, Inc.GLOO$3.13+0.48%189$271.85M$2.60 - $9.980.00%
826Gain Therapeutics, Inc.GANX$1.140.00%43$49.75M$0.94 - $4.340.00%
827XCEL BRANDS INC.XELB$0.42-11.44%4.11K$2.89M$0.27 - $2.470.00%
828Kalaris Therapeutics, Inc.KLRS$1.920.00%384$45.71M$1.78 - $11.880.00%
829Biote Corp.BTMD$1.02-7.93%3.69K$29.31M$0.99 - $2.900.04%
830GSI TechnologyGSIT$3.24-1.67%6.56K$124.52M$2.97 - $13.000.00%
831PetMed Express, Inc.PETS$1.13+0.36%2.02K$24.39M$1.06 - $4.100.00%
832Eastern International Ltd.ELOG$0.86-5.09%11.88K$11.01M$0.40 - $2.830.00%
833Workhorse Group, Inc.WKHS$3.25-2.84%271$35.52M$2.31 - $12.960.00%
834Ionis Pharmaceuticals, Inc.IONS$28.32-0.37%18.14K$4.71B$27.75 - $86.740.00%
835Kyntra Bio, Inc.KYNB$3.72+3.11%19.11K$15.05M$3.50 - $9.700.00%
836Atlantic American Corp.AAME$1.18-2.73%276$23.97M$1.01 - $3.240.03%
837NeOnc Technologies Holdings, Inc.NTHI$4.63+1.64%21.17K$121.41M$2.50 - $12.000.00%
838Bright Minds Biosciences Inc.DRUG$23.59+0.73%2$229.54M$17.40 - $123.750.00%
839Inter & Co. Inc.INTR$3.89-3.31%77.65K$1.26B$3.75 - $10.360.00%
840Stran & Company, Inc.SWAG$1.320.00%1$24.60M$1.21 - $3.500.00%
841Centrus Energy Corp.LEU$108.99-2.25%10.32K$2.17B$84.86 - $345.600.00%
842Regencell Bioscience Holdings LimitedRGC$5.42+0.74%1.88K$2.69B$4.51 - $69.000.00%
843Camping World Holdings, Inc.CWH$4.46-1.35%131$284.74M$3.96 - $15.180.03%
844Gelteq LimitedGELS$0.42-3.45%2.44K$4.50M$0.39 - $2.010.00%
845United States Antimony CorporationUAMY$3.02-2.24%150.62K$452.00M$2.53 - $12.640.00%
846Tactical Resources Corp.TREO$2.84+0.85%610$26.82M$1.40 - $9.200.00%
847Rezolve AI PLCRZLV$1.29-4.48%540.00K$433.86M$1.16 - $4.970.00%
848Peraso, Inc.PRSO$0.38-1.30%7.82K$5.72M$0.32 - $2.160.00%
849Trump Media & Technology Group Corp.DJT$5.04-2.51%465.81K$1.40B$3.80 - $17.090.00%
850Coastal Financial CorporationCCB$44.00+1.39%0$672.66M$35.56 - $120.050.00%

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Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
ProMIS Neurosciences Inc. (PMN) currently shows a 52-week decline of 62.45% as of 2026-11-12 14:14 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.