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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.03%⁩, the S&P 500 down ⁦0.66%⁩, and the Nasdaq Composite down ⁦1.13%⁩. Market breadth is negative, with 4,687 stocks declining versus 424 advancing, pointing to a broadly bearish bias.

Dow Jones
52,471.95
Change
-14.54-0.03%
S&P 500
7,568.85
Change
-50.53-0.66%
Nasdaq Composite
25,175.656
Change
-290.533-1.13%
24H Gainers
424
24H Losers
4,687

52 Week Gainers

#Stock52 Week Range
4251CytoMed Therapeutics LimitedGDTC$0.82-2.16%21$9.67M$0.68 - $2.290.00%
4252AGNT, Inc.AGNT$2.79-4.62%81.06K$459.55M$2.75 - $7.060.07%
4253Synlogic, Inc.SYBX$0.000.00%0$0$0.54 - $1.860.00%
4254Phathom Pharmaceuticals, Inc.PHAT$6.16+0.28%25.19K$500.51M$5.01 - $18.310.00%
4255Universe Pharmaceuticals Inc.UPC$1.55-1.02%1.16K$872.61K$1.33 - $17.960.00%
4256BCP Investment CorporationBCIC$5.53-19.63%94.65K$68.53M$5.11 - $13.500.25%
4257Instil Bio, Inc.TIL$6.31-0.22%296$42.77M$5.56 - $15.880.00%
4258Terra Innovatum Global N.V.NKLR$2.40-1.28%19.23K$296.14M$1.93 - $7.920.00%
4259Mesa Royalty TrustMTR$1.97-0.86%157$3.67M$1.85 - $5.830.00%
4260Artivion, Inc.AORT$20.00+0.70%7.59K$974.88M$19.16 - $48.250.00%
4261Altimmune, Inc.ALT$1.77-8.79%617.49K$345.07M$1.76 - $6.440.00%
4262Rein Therapeutics, Inc.RNTX$0.610.00%125$52.45M$0.54 - $2.100.00%
4263Citius Oncology, Inc.CTOR$0.56+1.26%341$52.16M$0.49 - $1.830.00%
4264Janux Therapeutics, Inc.JANX$11.89-4.16%66.68K$726.86M$11.59 - $35.340.00%
4265Eve Holding, Inc.EVEX$1.89-1.55%13.04K$657.27M$1.41 - $5.160.00%
4266TMC the metals company Inc.TMC$2.35-3.26%244.80K$1.04B$1.91 - $10.050.00%
4267eGain CorporationEGAN$6.28+0.80%977$158.97M$5.02 - $15.620.00%
4268WF International LimitedWXM$2.450.00%2.25K$7.64M$1.27 - $12.800.00%
4269ProKidney Corp.PROK$1.11-2.28%6.86K$232.38M$0.87 - $2.880.00%
4270AIOS Tech Inc.AIOS$9.13+0.83%252$29.65M$6.54 - $33.870.00%
4271Atlantic American Corp.AAME$1.24+2.98%620$25.37M$1.01 - $3.240.03%
4272Voyager Therapeutics, Inc.VYGR$1.76-7.32%37.80K$109.59M$1.68 - $5.480.00%
4273Figma, Inc.FIG$18.21-1.42%421.15K$10.39B$16.60 - $45.420.00%
4274Metagenomi Therapeutics, Inc.MGX$0.77+1.19%42.93K$29.01M$0.60 - $2.010.00%
4275Electra Battery Materials CorporationELBM$0.42-0.47%18.12K$45.49M$0.37 - $1.250.00%
4276QVC Group, Inc.QVCG$8.04-0.58%553$404.00M$6.80 - $20.000.00%
42775E Advanced Materials, Inc.FEAM$1.89-0.79%23.56K$93.56M$0.90 - $4.640.00%
4278Ebang International Holdings Inc.EBON$1.72+2.01%49$8.60M$1.35 - $4.200.00%
4279CoinShares PLCCSHR$3.54-3.91%3.60K$499.45M$3.50 - $10.430.00%
4280MoneyHero LimitedMNY$0.570.00%359$17.73M$0.38 - $1.600.00%
4281NuSkin Enterprises, Inc.NUS$3.94-1.03%8.02K$191.83M$3.85 - $11.670.06%
4282ERock, Inc.EROC$7.69-9.40%288.96K$397.44M$6.41 - $20.700.00%
4283Ballard Power Systems Inc.BLDP$1.41-5.32%127.64K$493.97M$1.40 - $6.570.00%
4284Zillow Group, Inc.Z$29.43+0.58%38.80K$5.24B$26.67 - $77.070.00%
4285Fair Isaac CorporationFICO$725.87+0.12%6.17K$15.68B$586.05 - $1,858.910.00%
4286TSS, Inc.TSSI$6.59-2.70%33.70K$185.88M$5.90 - $17.490.00%
4287InspireMD, Inc.NSPR$0.73-8.42%18.93K$33.89M$0.43 - $2.220.00%
4288Coherus Oncology, Inc.CHRS$0.55-9.95%222.81K$85.28M$0.55 - $2.620.00%
4289Franklin Wireless Corp.FKWL$2.070.00%266$24.39M$2.05 - $5.190.02%
4290Oxford Square Capital Corp.OXSQ$0.80-0.75%56.07K$96.77M$0.78 - $2.010.38%
4291Oculis Holding AGOCS$7.64+0.20%5.94K$443.29M$6.78 - $34.480.00%
4292Owlet, Inc.OWLT$4.45-3.05%1.47K$130.04M$4.02 - $16.940.00%
4293O-I Glass, Inc.OI$5.22+0.61%23.64K$803.43M$4.83 - $16.910.00%
4294GDEV Inc.GDEV$9.04-1.87%16$164.17M$8.50 - $25.030.00%
4295HIVE Digital Technologies LtdHIVE$1.65-4.01%521.28K$456.32M$1.58 - $5.340.00%
4296Foxx Development Holdings Inc.FOXX$1.36-1.09%9.60K$11.32M$1.28 - $7.900.00%
4297WM Technology, Inc.MAPS$0.000.00%0$0$0.18 - $1.210.05%
4298Workhorse Group, Inc.WKHS$3.35+0.15%4.10K$36.61M$2.31 - $12.960.00%
4299Aware Inc.AWRE$0.97+2.31%92$21.28M$0.82 - $2.520.00%
4300Vulcan Infrastructure and Power Inc.VIP$0.98+0.41%2.35K$15.40M$0.93 - $2.790.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
CytoMed Therapeutics Limited (GDTC) currently leads with a 52-week gain of 57.67% as of 2026-11-12 14:35 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.