52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 200 are advancing while 4,888 are declining, suggesting a mixed market tone.

Dow Jones

52,486.49

Change

+254.6+0.49%

S&P 500

7,619.38

Change

+98.45+1.31%

Nasdaq Composite

25,466.189

Change

+400.315+1.60%

24H Gainers

200

24H Losers

4,888

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
5051	Medicus Pharma LtdMDCX	$1.69	0.00%	517	$3.20M	$1.63 - $127.50	0.00%
5052	Instinct Bio Technical Company Holdings Inc.BIOT	$0.21	+0.48%	223	$5.38M	$0.17 - $50.00	0.00%
5053	Park Ha Biological Technology Co., Ltd.BYAH	$1.52	+4.25%	4.38K	$1.73M	$1.39 - $116.88	0.00%
5054	CEMTREX INC.CETX	$0.64	+0.31%	13.45K	$1.11M	$0.57 - $97.00	0.00%
5055	LZ Technology Holdings LimitedLZMH	$0.84	-1.99%	233	$6.58M	$0.66 - $65.60	0.00%
5056	Mint Incorporation LimitedMIMI	$0.96	+9.90%	900.98K	$12.13M	$0.61 - $76.80	0.00%
5057	IM Cannabis Corp.IMCC	$0.54	-8.77%	7.26K	$891.29K	$0.54 - $62.40	0.00%
5058	Meiwu Technology Company LimitedWNW	$2.01	+2.61%	10.10K	$52.82M	$1.80 - $1,352.00	0.00%
5059	Global Mofy AI LimitedGMM	$0.97	+0.62%	243	$9.31M	$0.83 - $92.50	0.00%
5060	Diginex LimitedDGNX	$1.22	+0.91%	9.33K	$33.50M	$0.85 - $144.48	0.00%
5061	Lichen China LimitedLICN	$0.04	+4.31%	19.32M	$627.59K	$0.04 - $9.49	0.00%
5062	Functional Brands, Inc.MEHA	$0.00	-55.31%	0	$0	$0.00 - $0.62	0.00%
5063	Treasure Global Inc.TGL	$0.18	+1.10%	29.02K	$944.26K	$0.17 - $58.00	0.00%
5064	Nexera Technologies LtdNEXR	$2.08	+2.72%	1.74K	$1.09M	$1.70 - $299.19	0.00%
5065	Huachen AI Parking Management Technology Holding Co., Ltd.HCAI	$3.15	+2.01%	800	$1.90M	$2.01 - $519.80	0.00%
5066	zSpace, Inc.ZSPC	$0.00	0.00%	0	$0	$0.05 - $21.25	0.00%
5067	20/20 Biolabs, Inc.AIDX	$0.21	+3.92%	34.43K	$2.67M	$0.18 - $50.00	0.00%
5068	Propanc Biopharma, Inc.PPCB	$1.83	-3.89%	2.03K	$1.89M	$1.63 - $315.00	0.00%
5069	NextNRG, Inc.NXXT	$1.79	+2,961.66%	97.07M	$4.40M	$0.12 - $222.00	0.00%
5070	Linkers Industries LimitedLNKS	$0.85	+0.12%	4.24K	$1.29M	$0.56 - $420.00	0.00%
5071	Sunshine Biopharma Inc.SBFM	$2.71	-1.63%	2.13K	$2.07M	$2.53 - $464.00	0.00%
5072	GlucoTrack, Inc.GCTK	$1.37	-33.66%	4.12M	$0	$0.28 - $207.00	0.00%
5073	Parabolic Technologies, Inc.PARA	$0.13	+53.48%	377.81M	$64.78K	$0.06 - $19.40	0.00%
5074	SU Group Holdings LimitedSUGP	$1.32	-7.60%	3.54K	$2.41M	$1.26 - $291.00	0.00%
5075	IP Strategy Holdings, Inc.IPST	$2.09	-0.48%	267	$2.08M	$1.54 - $301.60	0.00%
5076	T3 Defense Inc.DFNS	$2.08	-12.17%	143.96K	$7.02M	$1.75 - $335.00	0.00%
5077	GeoVax Labs, Inc. NewGOVX	$2.08	-6.29%	16.74K	$25.46M	$1.84 - $311.94	0.00%
5078	Onfolio Holdings Inc.ONFO	$0.38	+3.84%	1.54K	$947.21K	$0.32 - $123.92	0.58%
5079	Interactive Strength Inc.TRNR	$1.35	+8.43%	2.96K	$2.19M	$1.11 - $205.94	0.00%
5080	U Power LimitedUCAR	$2.85	-2.20%	2	$5.59M	$2.34 - $436.00	0.00%
5081	Nuwellis, Inc.NUWE	$5.36	-2.42%	1.21K	$2.00M	$2.52 - $1,556.07	0.00%
5082	Wellchange Holdings Company LimitedWCT	$3.61	-6.01%	15.80K	$5.46M	$1.96 - $675.00	0.00%
5083	Wetour Robotics LimitedWETO	$0.65	+1.42%	41.81K	$695.18K	$0.55 - $139.99	0.00%
5084	Inno Holdings Inc.INHD	$2.81	+2.11%	657	$7.08M	$1.01 - $1,656.00	0.00%
5085	Clearmind Medicine Inc.CMND	$5.28	+7.00%	404	$2.68M	$4.93 - $2,076.80	0.00%
5086	Enlivex Ltd.ENLV	$1.27	-0.24%	176	$1.95M	$1.18 - $434.40	0.00%
5087	Lucas GC LimitedLGCL	$1.61	-1.82%	2.72K	$1.78M	$1.07 - $372.50	0.00%
5088	Kaixin HoldingsKXIN	$2.63	-2.59%	15.30K	$52.79M	$0.54 - $576.00	0.00%
5089	Top Wealth Group Holding LimitedTWG	$2.71	+1.96%	1.61K	$2.07M	$2.40 - $2,636.00	0.00%
5090	KALA BIO, Inc.KALA	$0.17	-3.41%	55.82K	$3.29M	$0.11 - $95.50	0.00%
5091	Creative Media & Community Trust CorporationCMCT	$4.31	+0.16%	6.31K	$11.88M	$1.77 - $1,441.00	1.19%
5092	Zhibao Technology Inc.ZBAO	$0.22	-3.06%	294.00K	$5.93M	$0.19 - $67.00	0.00%
5093	Silexion Therapeutics Corp.SLXN	$3.13	-5.78%	4.39K	$47.59M	$2.57 - $777.12	0.00%
5094	Lakewood-Amedex Biotherapeutics Inc.LABT	$0.37	-2.39%	238.65K	$990.53K	$0.17 - $98.20	0.00%
5095	Freight Technologies, Inc.FRGT	$0.89	+2.08%	2.62K	$61.48K	$0.79 - $342.50	0.00%
5096	Fitness Champs Holdings LimitedFCHL	$0.69	-5.34%	11.38K	$916.92K	$0.52 - $184.50	0.00%
5097	Elme CommunitiesELME	$0.07	-96.19%	235.55M	$5.99M	$0.06 - $17.68	0.00%
5098	NETCLASS TECHNOLOGY INC.NTCL	$0.20	-8.11%	190.89K	$260.89K	$0.18 - $155.00	0.00%
5099	DarkIris Inc.DKI	$1.48	-3.71%	20.92K	$92.29K	$1.33 - $968.00	0.00%
5100	Karyopharm Therapeutics Inc.KPTI	$0.02	-8.00%	21.07M	$415.07K	$0.02 - $10.99	0.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Medicus Pharma Ltd (MDCX) currently leads with a 52-week gain of 98.59% as of 2026-11-12 13:31 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

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Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.