52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are mixed today. The Dow Jones is ⁦+0.49%⁩, the S&P 500 is ⁦+1.31%⁩, and the Nasdaq Composite is ⁦+1.60%⁩. Across individual stocks, 373 are advancing while 4,717 are declining, suggesting a mixed market tone.

Dow Jones

52,486.49

Change

+254.6+0.49%

S&P 500

7,619.38

Change

+98.45+1.31%

Nasdaq Composite

25,466.189

Change

+400.315+1.60%

24H Gainers

373

24H Losers

4,717

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
451	Protagonist Therapeutics, Inc.PTGX	$135.34	+0.42%	1.47K	$8.76B	$77.00 - $160.81	0.00%
452	Alerus Financial CorporationALRS	$34.32	-0.50%	167	$855.51M	$20.93 - $35.49	0.02%
453	Quanex Building Products CorporationNX	$21.01	-0.85%	134.92K	$962.99M	$11.04 - $23.33	0.02%
454	Eastern CompanyEML	$31.42	-0.47%	0	$189.08M	$17.61 - $33.86	0.01%
455	AMES National Corp.ATLO	$33.89	-0.57%	2	$300.18M	$20.51 - $35.45	0.03%
456	BRC Group Holdings, Inc.RILYZ	$16.75	0.00%	0	$0	$8.65 - $21.10	0.00%
457	Usio, Inc.USIO	$2.27	-0.70%	1.78K	$64.83M	$1.03 - $3.29	0.00%
458	MOOG INC CL BMOG.B	$349.88	+1.09%	2	$1.13B	$220.00 - $450.00	0.00%
459	Rogers CorporationROG	$130.82	0.00%	7	$2.33B	$75.14 - $169.00	0.00%
460	Xenia Hotels & Resorts, Inc.XHR	$22.02	+0.84%	0	$2.03B	$13.38 - $22.34	0.02%
461	ALLISON TRANSMISSION HOLDINGS, INC.ALSN	$130.28	+0.31%	147	$10.70B	$78.77 - $137.62	0.01%
462	Cenovus Energy Inc.CVE	$28.79	+1.41%	11.56K	$52.02B	$15.63 - $34.16	0.00%
463	DHT HOLDINGS, INC.DHT	$21.58	-1.16%	45.97K	$3.47B	$11.64 - $26.91	0.02%
464	IDT CorporationIDT	$82.99	-0.20%	104.87K	$1.93B	$46.48 - $84.56	0.00%
465	Guardant Health, Inc.GH	$155.27	+0.47%	54.72K	$20.84B	$74.55 - $191.05	0.00%
466	Venture Global, Inc.VG	$12.89	+1.74%	74.26K	$29.50B	$5.72 - $17.62	0.01%
467	Vogenx Inc.VOGX	$20.60	-0.67%	0	$272.44M	$12.95 - $38.41	0.00%
468	Reliance, Inc.RS	$437.40	+1.39%	2.90K	$22.28B	$263.12 - $454.93	0.00%
469	Guardian Pharmacy Services, Inc.GRDN	$49.98	+0.06%	517	$3.16B	$26.34 - $50.59	0.00%
470	DARLING INGREDIENTS INC.DAR	$54.65	+0.28%	19	$8.62B	$31.81 - $69.98	0.00%
471	Danaos CorporationDAC	$150.70	0.00%	234	$2.74B	$92.02 - $172.76	0.00%
472	InnovAge Holding Corp.INNV	$9.00	-5.26%	192	$1.23B	$4.70 - $12.64	0.00%
473	Littelfuse Inc.LFUS	$389.48	-2.13%	4.25K	$9.89B	$233.36 - $500.57	0.01%
474	Sphere Entertainment Co.SPHR	$126.60	+0.13%	558	$3.72B	$73.03 - $181.63	0.00%
475	Foster (Lb) CoFSTR	$42.31	-0.18%	0	$445.12M	$25.66 - $45.81	0.00%
476	Accelerant HoldingsARX	$19.89	-0.20%	511.18K	$4.32B	$9.18 - $19.91	0.00%
477	Trio-Tech InternationalTRT	$5.25	0.00%	6.31K	$54.28M	$3.25 - $21.38	0.00%
478	Permian Basin Royalty TrustPBT	$30.77	0.00%	75	$1.43B	$16.25 - $37.00	0.00%
479	Braze, Inc.BRZE	$46.32	-0.51%	8.00K	$5.26B	$15.26 - $46.71	0.00%
480	Slide Insurance Holdings, Inc.SLDE	$26.31	+0.27%	2.74K	$3.07B	$15.11 - $29.14	0.00%
481	Bloom Energy CorporationBE	$199.63	-5.00%	743.72K	$59.02B	$75.70 - $351.28	0.00%
482	USA TODAY Co., Inc.TDAY	$7.25	0.00%	18	$1.06B	$4.33 - $9.21	0.00%
483	Suncor Energy, Inc.SU	$69.66	+1.41%	329	$80.71B	$42.09 - $80.25	0.02%
484	NWPX Infrastructure, Inc.NWPX	$91.64	+0.27%	407	$882.54M	$53.15 - $152.03	0.00%
485	Twin Disc, IncorporatedTWIN	$25.04	0.00%	6	$364.05M	$14.22 - $29.23	0.01%
486	Biogen Inc.BIIB	$254.08	+0.40%	476	$37.56B	$158.05 - $261.00	0.00%
487	PDF Solutions Inc.PDFS	$40.87	-1.94%	6.18K	$1.63B	$23.55 - $71.69	0.00%
488	OUTFRONT Media Inc.OUT	$33.77	+0.27%	11	$5.95B	$21.27 - $34.96	0.04%
489	Bankwell Financial Group Inc.BWFG	$70.92	+0.23%	7	$565.41M	$43.44 - $74.46	0.01%
490	TD SYNNEX CorporationSNX	$239.89	+0.35%	25	$19.14B	$142.22 - $298.77	0.01%
491	Avient CorporationAVNT	$46.23	0.00%	70	$4.24B	$27.48 - $49.08	0.02%
492	The Gorman-Rupp CompanyGRC	$70.25	-0.25%	5	$1.86B	$42.31 - $92.78	0.01%
493	Immunovant, Inc.IMVT	$36.70	-0.88%	9.33K	$7.58B	$21.86 - $45.42	0.00%
494	Wabash National Corp.WNC	$12.03	0.00%	8	$489.88M	$6.63 - $14.55	0.03%
495	CarMax Inc.KMX	$53.89	0.00%	61	$7.65B	$31.95 - $65.28	0.00%
496	Equillium, Inc.EQ	$1.45	+1.83%	6	$91.69M	$0.76 - $3.54	0.00%
497	CF Bankshares Inc.CFBK	$35.30	-0.02%	0	$226.44M	$22.45 - $38.11	0.01%
498	Hasbro, Inc.HAS	$123.74	-0.12%	641	$17.31B	$74.78 - $124.76	0.02%
499	Alpha and Omega Semiconductor LimitedAOSL	$29.70	-2.54%	3.93K	$900.06M	$17.01 - $54.34	0.00%
500	ConocoPhillipsCOP	$139.20	+0.14%	9.17K	$167.23B	$85.70 - $154.28	0.03%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Protagonist Therapeutics, Inc. (PTGX) currently leads with a 52-week gain of 59.51% as of 2026-11-12 13:49 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

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Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.